• Outbreaks of carbapenem resistant A baumannii carrying blaOX

  2019-04-29

  

  Outbreaks of carbapenem-resistant A. baumannii carrying blaOXA-23-like were discovered in different countries, and the range of blaOXA-23-like has been reported from 31% to 100% worldwide. In our study, the vast majority of isolates (70%) were positive for blaOXA-23-like. Moreover, we found that 20%

• br CaMKII and heart failure

  2019-04-29

  

  CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com

• The incidence of pacemaker lead fracture is about

  2019-04-29

  

  The incidence of pacemaker lead fracture is about 2.6–3.6% [3,4]. However, most cases of pacemaker lead fracture occur within the pacemaker pocket or the subclavian vein between the mtor pathway and the first rib [3,4], and fracture at the tricuspid valve level is rare [5–7]. When lead fracture occu

• br The L type calcium channel LTCC in heart

  2019-04-29

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• Una soluci n te rico metodol gica

  2019-04-29

  

  Una solución teórico-metodológica sería adscribir a las concepciones de cierto “realismo de larga duración”, o a las propuestas por Erich Auerbach respecto de las posibilidades de leer la literatura occidental en función de este modo específico de la representación. Tentadora y pertinente en término

• br Conclusiones finales As resulta necesario trabajar

  2019-04-29

  

  Conclusiones finales Así, resulta necesario trabajar y fortalecer políticas comunes de los países que tengan como fin la equidad social para reducir o eliminar la pobreza y la educación para un buen uso de los recursos naturales. Asimismo, se propone avanzar en la unificación de legislaciones y c

• Resulta interesante contrastar las opiniones de analistas

  2019-04-29

  

  Resulta interesante contrastar las opiniones de analistas e investigadores cubanos con estadounidenses, pues si bien mantienen coincidencias, también parten desde luego de sus ámbitos geográficos. El mismo Lowenthal, quien es miembro no residente de la Brookings Institution y ex director fundador de

• Las soluciones de Barros de teorizar la noci n

  2019-04-29

  

  Las soluciones de Barros de teorizar la noción de underdogs con la ayuda de categorías de Rancière implica no sólo sacar la teoría de Laclau de su formalismo sino también inscribir algún tipo de fundamento ya que el autor francés basa la emergencia del desacuerdo en el supuesto de igualdad-libertad

• br Methods The Spanish GEM

  2019-04-29

  

  Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc

• Studies using fixed site monitoring data rather than persona

  2019-04-29

  

  Studies using fixed-site monitoring data rather than personal monitoring data are subject to misclassification of the exposure because fixed site monitors do not account for individual mobility that affect exposure. Although, this typically results in non-differential exposure misclassification that

• br Universal health coverage UHC as a target in

  2019-04-29

  

  Universal health coverage (UHC) as a target in the health Sustainable Development Goals (SDGs) empowers countries to seize the exceptional chance to reach a great convergence in global health. In recent years, many countries have adopted UHC as an aspiration for national policy and WHO pointed out

• br The Article by James Platts Mills and

  2019-04-28

  

  The Article by James Platts-Mills and colleagues (September, 2015), highlights the burden of diarrhoeal disease in young children in developing countries and also demonstrates the effect that seasonal variations have on multiple causative pathogens. Infectious gastroenteritis contributes significa

• Our investigation suggests that cardiac pacing improves not

  2019-04-28

  

  Our investigation suggests that cardiac pacing improves not only CSA but also OSA. The mechanism by which SDB is improved is unclear. CSA might be improved by reduction of periodic variations in heart rate, which are increased by Romidepsin Supplier and may result in part from changes in autonomic

• br Diagnostic criteria Brugada syndrome is definitively diag

  2019-04-28

  

  Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s

• The exhibited efficacies of bone targeting

  2019-04-28

  

  The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b

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