• It is important to know whether pilsicainide can

  2019-06-13

  

  It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G

• El proyecto literario del conocido escritor mexicano

  2019-06-13

  

  El proyecto literario del conocido escritor mexicano Ignacio Manuel Altamirano (1834–1893) ha sido ampliamente documentado en los estudios del siglo . Su propósito fue claro: instruir e inspirar al pueblo mexicano, cansado y desilusionado por la situación inestable del México decimonónico y por el s

• The review Bile acid receptor link nutrient

  2019-06-13

  

  The review “Bile ppar antagonist receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic, but

• Efforts to estimate the global

  2019-06-13

  

  Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me

• br This year marks years since countries signed

  2019-06-13

  

  This year marks 20 years since 189 countries signed the Beijing Declaration and Platform for Action and committed to prioritisation of women\'s empowerment and gender equality. Yet a recently released UN analysis shows that violence against women persists at “alarmingly high levels”. Worldwide, on

• La representaci n colectiva de los ind genas se caracteriza

  2019-06-13

  

  La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye thymidylate synthase inhibitors resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las opo

• Desde ese ngulo es visible c mo la Antig edad

  2019-06-13

  

  Desde ese ángulo es visible cómo la Antigüedad vivía en la medida que era apropiada por los criollos: la gramática latina de Andrés Bello fue novedosa en cuanto explicó la lengua desde el castellano actual (y americano), con la conciencia que éste tenía una estructura distinta. Los símbolos grecorro

• Como tercera cuesti n y de

  2019-06-13

  

  Como tercera cuestión, y de suma relevancia, la economía argentina fue receptora de una muy pequeña inversión china, contrariamente bradykinin receptor antagonist la expectativa generada por la visita al país del presidente Hu Jintao, en noviembre de 2004. Se había supuesto, desde el gobierno argent

• Seg n Patricia Fagen en su estudio cl sico

  2019-06-13

  

  Según Patricia Fagen, en su estudio clásico sobre el exilio español, “un numero sorprendente de jóvenes participaron en el Movimiento 1959 y muchos más hubieran participado si hubiesen creído que había algo significativo con lo que hubieran podido contribuir”. El espíritu de ruptura con las disputas

• If a structurally normal patient

  2019-06-12

  

  If a structurally normal patient with polymorphic VT/VF storm has a completely normal baseline ECG, the possible diagnosis includes CPVT and idiopathic VF. CPVT is an inherited disorder of intracellular Ca2+ handling, which can cause polymorphic VT/VF storms [10]. Abnormal SR Ca2+ release from defec

• In conclusion a rare KCNE D N

  2019-06-12

  

  In conclusion, a rare KCNE1-D85N polymorphism may modify the LQTS phenotype in combination with other pathogenic LQTS-related gene mutations. Disclosures Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is observed in 10–30% of patients with symptomatic glycoge

• br Practical use of the Sweet Tip screw

  2019-06-12

  

  Practical use of the Sweet Tip™ screw-in lead Entrapment of screw-in lead Entrapment is a relatively rare complication that can occur with the Sweet Tip™ screw-in lead as often as with other types of leads [13,14]. In the Sweet Tip™ lead, the helix might become exposed in the atrium and the ri

• br What is the best pacing algorithm for

  2019-06-12

  

  What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac

• All patients with symptomatic cardiac AL amyloidosis had poo

  2019-06-12

  

  All 4 patients with symptomatic cardiac AL amyloidosis had poor prognoses. The median survival period for these 4 patients was 12.3 months (minimum=4 months, maximum=28 months) (Table 1). The patient in Case 2, whose BNP level was the highest of the 4 patients, had the shortest survival period. Howe

• br Results Twenty seven bone

  2019-06-12

  

  Results Twenty-seven bone lesions were analyzed in 27 patients. Twelve of the patients were female and 15 were male. The mean age of the patients was 58 years with a range of 21–84 years. Ten lesions were determined to be malignant and 17 benign. Benign lesions of bone dropped in signal on out-of

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