• CP-673451 MCL has a poor long term response

  2019-06-14

  

  MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens

• A number of clinical studies have confirmed the

  2019-06-14

  

  A number of clinical studies have confirmed the beneficial effect of ranolazine in either prevention or treatment of AF. The first strong evidence was provided by MERLIN-TIMI 36 trial [the Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST-Elevation Acute Coronary Syndrome–Thrombolysis

• Como ha destacado Leonardo Tarife

  2019-06-14

  

  Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac

• Se empieza entonces a usar el clavel como un

  2019-06-14

  

  Se empieza, entonces, 5ht receptors usar el clavel como un elemento independiente e individual de la foto de Calanchina, sin desarticularse por completo de la figura de Robin, ya que casi se convierte en un atributo religioso que estará presente en la mayoría de las imágenes donde se le represente,

• Through analyses of data from surveys that

  2019-06-14

  

  Through analyses of data from surveys that used similar measures, methods, and ethical standards across 44 countries, Heise and Kotsadam have taken an important step towards an improved understanding of intimate partner violence and informing interventions. However, much work remains to be done. In

• Y sin embargo de esos pueblos presuntamente reaccionarios po

  2019-06-14

  

  Y sin embargo, de esos pueblos presuntamente reaccionarios por naturaleza provienen muchos de los más importantes escritores de La Tribune des Peuples. Los escritos de esos colaboradores tienen como fin afirmar la historicidad de esos pueblos y la continuidad de sus luchas. Los radicales de La Tribu

• El otro paradigma cuyo alcance y magnitud exige atenci

  2019-06-14

  

  El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso GSK503 la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlemar Chiamp

• br Hacia un monote smo ta

  2019-06-14

  

  Hacia un monoteísmo taíno Debido al hecho de que la irreductible diversidad de los cemíes parece demasiado peligrosa para ser comparada con la noción antigua de divinidad, la Relación trata de proponer, aunque de manera discreta, otra forma de interpretación: es decir, la búsqueda de las huellas

• GS-9620 Although second malignancies are increasingly observ

  2019-06-14

  

  Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo

• Abstract Background Substantial progress has been made in re

  2019-06-13

  

  Abstract Background Substantial progress has been made in reducing the incidence and prevalence of malaria. In 2016, 111 countries have eliminated malaria and another 35 countries, are making progress toward elimination of the disease. However, little is known about how much governments and donors

• Between February and November we conducted a priority settin

  2019-06-13

  

  Between February and November, 2015, we conducted a priority-setting exercise to set research priorities for ECD to 2025. This is part of WHO\'s larger initiative to set priorities for maternal, newborn, child, and adolescent health. We used the Child Health and Nutrition Research Initiative (CHNRI)

• In a study of the atrial

  2019-06-13

  

  In a study of the atrial pacing preference (APP) algorithm, Ogawa et al. [12] randomly programmed pacemakers as APP OFF and APP ON at 3 different settings (8, 16, and 33 cycles). The authors found that the most effective setting differed according to the patient and thus concluded that this therapy

• Curative treatments which include surgical resection percuta

  2019-06-13

  

  Curative treatments, which include surgical resection, percutaneous ablation and liver transplantation, were considered as the optimal treatment for patients with very early/early stage HCC by BCLC criteria. Furthermore, advances in liver surgery make the resection of large and/or multifocal HCC pos

• Recently denosumab demonstrated a significant

  2019-06-13

  

  Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R

• It is important to know whether pilsicainide can

  2019-06-13

  

  It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G

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