• br Experimental Procedures br Acknowledgments br Bisphenol A

  2020-11-02

  

  Experimental Procedures Acknowledgments Bisphenol A (BPA) has been recognized as one of the most potent endocrine disruptors, functioning even at very low doses. Although it is anticipated that bapta am australia receptor (ER) would mediate these effects of low-dose BPA, studies revealed th

• TgTCEA from petals TgTCEA and TgTCEB from pollen grains

  2020-11-02

  

  TgTCEA from petals (TgTCEA1) and TgTCEB from pollen grains (TgTCEB1) were used throughout the study. The recombinant enzymes were expressed in , and purified as the His-tag-free forms as described previously., Enzyme reactions were performed at 4 mM substrates under the same conditions as described

• Human neutrophil elastase HNE is a

  2020-11-02

  

  Human neutrophil elastase (HNE) is a serine protease central to the pathology in a wide range of diseases including chronic wounds, cystic fibrosis, and acute respiratory distress syndrome (Owen, 2008). Although neutrophil proteases are necessary for completion of wound healing, HNE is secreted in h

• Studies of LRRK tagged with green fluorescent protein reveal

  2020-10-31

  

  Studies of LRRK2 tagged with green fluorescent protein revealed the presence of monomeric LRRK2 in the BMS 470539 dihydrochloride of living cells, while LRRK2 oligomers were found in the proximity of the plasma membrane, suggesting that both oligomerization status and compartmentalization of LRRK2 d

• Several of the plant extracts that showed interaction with

  2020-10-31

  

  Several of the plant extracts that showed interaction with ERα and ERβ have differing reports concerning estrogenicity and receptor binding. Extracts of dong quai stimulated MCF-7 proliferation but failed to increase uterine weight or transactivate either ERα or ERβ in a cell assay (Amato et al., 20

• Another important consideration with respect

  2020-10-31

  

  Another important consideration with respect to drug conditioning suggested by the present findings is the observation of an attenuated g protein coupled receptors on the second extinction trial. Seemingly, if ERK measurements were made following a partial reduction in the conditioned response the E

• Piperlongumine australia is one of the few parasites that ca

  2020-10-31

  

  is one of the few parasites that can be encysted and excysted and we tested the localization and role of HA-tagged gEno in both differentiations, using a recently developed integrated vector that introduces a C-terminal triple HA tag under the selection marker puromycin . The localization of HA-tagg

• While PRRSV has been recently shown to induce SGs

  2020-10-31

  

  While PRRSV has been recently shown to induce SGs, the exact nature of SG formation and its underlying mechanism of regulating antiviral immune response during PRRSV infection remain unclear (Zhou et al., 2017). Formation of PRRSV-induced SGs was observed in MARC145 boc boc (Chen et al., 2018) and

• Mother rats acutely treated with quinpirole and mg kg decrea

  2020-10-31

  

  Mother rats acutely treated with quinpirole (0.5 and 1.0 mg/kg) decreased the pup exploration time but increased the object exploration, so they showed a significantly lower pup preference ratio. They also showed impaired maternal performance in the home cage, consistent with our previous study (Zha

• All DGKs have at least

  2020-10-31

  

  All DGKs have at least two cysteine-rich regions homologous to the C1A and C1B motifs of PKCs [26]. In theory, these domains may bind DAG, perhaps localizing DGKs to where DAG accumulates. However, no DGK C1 domain has so far been conclusively shown to bind DAG. In fact, structural predictions sugge

• The significance of the two biomarkers for

  2020-10-30

  

  The significance of the two biomarkers for the detection of Aspergillus antigen and DNA in the sputum of patients cannot be over-emphasised. The mean GMI value was higher among CPA patients than the ABPA. This might not be unconnected with the fact that CPA is associated with lung damage and pre-exi

• Furthermore many intermediate plants did

  2020-10-30

  

  Furthermore, many intermediate plants did not show additive combinations of parental allozymes, which would be expected in F1 hybrids. The absence of some characteristic parental bands suggests that sexual reproduction has occurred among the hybrid plants. Genetic variations within and among the int

• br Transparency document br Introduction The cyclic nucleoti

  2020-10-30

  

  Transparency document Introduction The cyclic nucleotide adenosine 3′,5′-cyclic monophosphate (cAMP) exerts both an endothelium-dependent and an endothelium independent vasorelaxant action in rat AH 7614 [1]. cAMP direct, endothelium-independent vasorelaxant effects have been attributed to se

• br O GlcNAcase Human OGA is

  2020-10-30

  

  O-GlcNAcase Human OGA is a multidomain protein with an N-terminal domain similar to glycoside hydrolase family 84 (GH84) enzymes, a stalk domain, a C-terminal pseudo histone acetyltransferase (HAT) domain, and several low-complexity regions (Figure 1f) [43]. A splice variant that lacks the HAT do

• Dual inhibition of ACE and NEP as

  2020-10-30

  

  Dual inhibition of ACE and NEP as a strategy for treating hypertension has been extensively investigated, including contributions from these laboratories through the discovery of Sampatrilat . Given that both targets are related zinc metalloproteinases, dual enzyme inhibition can be achieved within

14669 records 697/978 page Previous Next First page 上5页 696697698699700 下5页 Last page